Petr Volf

The paper investigates the role of Argonaute in controlling viral replication in Leishmania martiniquensis, finding that its loss reduces viral RNA abundance and disrupts small RNA accumulation.

This study identifies a pH-dependent kinase cascade in Leishmania that regulates differentiation into infectious stages, revealing key pathways for acid adaptation and transmission.

This study identifies Dicer-like 1 and Argonaute 1 as critical for controlling viral RNA levels in Leishmania guyanensis via a canonical RNA interference pathway.

The paper demonstrates successful gene editing in sand flies using CRISPR-Cas9 and PiggyBac to target olfactory and non-lethal phenotypic genes.

The paper identifies 34 transporter genes essential for Leishmania promastigote survival in sand flies, with V-ATPase subunits critical for parasite differentiation and life cycle progression.

This study examines how a sub-chromosomal deletion in Leishmania infantum affects parasite virulence, transmission, and drug resistance, suggesting it may enhance geographic spread.

This study shows that DOT1B is not essential for differentiation or macrophage infection in Leishmania mexicana, contrasting its essential role in Trypanosoma brucei.

This study identifies Chinese hamsters and Steppe lemmings as new animal models for studying Mundinia Leishmania species, showing susceptibility and infectiousness to sand flies.

This study uses 3D electron microscopy to analyze Leishmania mexicana cell cycle stages, revealing organelle duplication, segregation patterns, and metabolic adaptations in different environments.

The paper analyzes whole-genome sequences of Leishmania donovani isolates from Ethiopia to investigate hybridization patterns and recombination in natural populations.

The paper identifies sex determination genes in sand flies using genomics and transcriptomics, proposes a model for their sex determination cascade, and characterizes a novel transformer homolog.