Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against Senescence
Jinsen Lu, Srinivasa R. Rao, Helen J. Knowles, Haoqun Zhan, Beatriz Gámez, Eleanor Platt, Lucy R. Frost, Tiffany-Jayne Allen, Gayle B. Marshall, K. Huber, Ludwig G. Bauer, Iolanda Vendrell, Benedikt Mathias Kessler, Anne M. Horne, Ian R. Reid, , James Edwards
This study shows bisphosphonates reduce senescence markers and alter proteomes in multiple cell types, suggesting anti-ageing effects beyond bone health.
bioRxiv · Mar 25, 2025 · PreprintCell Biology