Author

Helen J. Knowles

University of OxfordORCID 0000-0002-9575-6067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne M. HorneiD· 1 shared Beatriz Gámez· 1 shared Benedikt Mathias KessleriD· 1 shared C. BountraiD· 1 shared Eleanor Platt· 1 shared Frank H. EbetinoiD· 1 shared Gayle B. MarshalliD· 1 shared Haoqun Zhan· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Anne M. HorneORCID

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1 paper

Recent·Most cited

Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against Senescence

Jinsen Lu, Srinivasa R. Rao, Helen J. Knowles, Haoqun Zhan, Beatriz Gámez, Eleanor Platt, Lucy R. Frost, Tiffany-Jayne Allen, Gayle B. Marshall, K. Huber, Ludwig G. Bauer, Iolanda Vendrell, Benedikt Mathias Kessler, Anne M. Horne, Ian R. Reid, , James Edwards

This study shows bisphosphonates reduce senescence markers and alter proteomes in multiple cell types, suggesting anti-ageing effects beyond bone health.

bioRxiv · Mar 25, 2025 · PreprintCell Biology