Trans-acting mutations reveal non-nuclear modulators of both intrinsic and extrinsic gene expression noise in a eukaryote.
Nena Martin, Julie Kleine-Schultjann, Elena París, Quentin Boussau, Agnès Dumont, Hélène Duplus‐Bottin, Margaux Prieux, Adelme Bazin, Laurent Modolo, Gaël Yvert, Patricia Jean Wittkopp, Fabien Duveau
The paper identifies trans-acting mutations in yeast that modulate gene expression noise in both intrinsic and extrinsic ways, revealing non-nuclear factors influencing nuclear gene expression.
bioRxiv · Nov 22, 2025 · PreprintGenetics