Margaux Prieux

Trans-acting mutations reveal non-nuclear modulators of both intrinsic and extrinsic gene expression noise in a eukaryote.

The paper identifies trans-acting mutations in yeast that modulate gene expression noise in both intrinsic and extrinsic ways, revealing non-nuclear factors influencing nuclear gene expression.

A temporary challenge by tumor cells can lead to a permanent partial-impairment of memory CD8 T cell function

This study compares memory CD8 T cells generated from tumor rejection and acute viral infection, finding that tumor-induced cells show persistent functional defects similar to exhaustion.

Memory-Phenotype Ly49+ CD8 T emerging from the thymus develop into two subsets with distinct immune functions

This study identifies two subsets of Ly49+ CD8 T cells developing in the thymus through agonist selection, which respond to bystander signals and some exhibit antiviral activity during infection.

A pivotal genetic program controlled by thyroid hormone during the maturation of GABAergic neurons in mice

This study identifies TR1-dependent gene regulation in GABAergic neurons during post-natal maturation, revealing a critical role for thyroid hormone in neurodevelopment.