Author

Jean-Philippe Goulet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alan HodgkinsoniD· 1 shared Andrés FinziiD· 1 shared Augustine Fert· 1 shared Brendan BelliD· 1 shared Christ Dominique Ngassaki Yoka· 1 shared Debashree ChatterjeeiD· 1 shared Elias Gbeha· 1 shared Elodie Hip-Ki· 1 shared

Activity by Year

2014-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

Alan HodgkinsonORCID

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2 papers

Recent·Most cited

REV-ERBα/β Targeting Transcriptionally Reprograms HIV-Infected CD4+ T-Cells for Increased Viral Reactivation but Limited Virion Spread

Christ Dominique Ngassaki Yoka, Jean-Philippe Goulet, Soumia Khalfi, Debashree Chatterjee, Tomas Raul Wiche Salinas, Yuwei Zhang, Laurence Raymond Marchand, Julie Moreaux, Jonathan Dias, Augustine Fert, Nicolas Chomont, Jonathan Richard, Andrés Finzi, Nicolas Cermakian, Brendan Bell, , Petronela Ancuța

This study shows that inhibiting REV-ERBβ increases HIV-1 reactivation in CD4+ T-cells but limits virion spread.

bioRxiv · Aug 24, 2026 · PreprintImmunology

Recombination impacts damaging and disease mutation accumulation in human populations

Julie Hussin, Alan Hodgkinson, Youssef Idaghdour, Jean-Christophe Grenier, Jean-Philippe Goulet, Elias Gbeha, Elodie Hip-Ki, Philip Awadalla

The paper shows that recombination rate influences the distribution of deleterious variants across the human genome, with low recombination regions enriched for disease-associated mutations.

bioRxiv · Sep 10, 2014Evolutionary Biology