Elisa Hawkins

Long-term dysregulation of histone acetylation, BDNF expression, and the hippocampal transcriptome in adult rats exhibiting a depressive-like phenotype following repeated chlorpyrifos exposure

This study shows that repeated chlorpyrifos exposure in rats leads to long-term epigenetic and transcriptional changes in the hippocampus, including reduced BDNF and altered neuronal plasticity pathways, associated with a depressive-like phenotype.

Assessment of pharmacokinetics, safety, and neuroprotective efficacy of an adjunct intramuscular verapamil therapy in a rat model of organophosphate DFP-induced status epilepticus

This study evaluates the safety, pharmacokinetics, and neuroprotective effects of intramuscular verapamil in a rat model of organophosphate-induced status epilepticus, showing improved brain levels and neuroprotection compared to oral administration.

SELECTIVE INHIBITION OF SOLUBLE TNF ATTENUATES HIPPOCAMPAL NEUROINFLAMMATION AND PSD-95 EXPRESSION TO IMPROVE NEUROLOGICAL FUNCTIONS IN A RAT MODEL OF GULF WAR ILLNESS

This study shows that selectively inhibiting soluble TNF with XPro1595 reduces neuroinflammation and improves neurological function in a rat model of Gulf War Illness.