Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters
Elisa Zanfrini, Manuj Bandral, Luka Jarc, Maria Alejandra Ramirez-Torres, Daniela Pezzolla, Vida Kufrin, Eva Rodríguez-Aznar, Ana Karen Mojica-Avila, Christian M. Cohrs, Stephan Speier, Katrin Neumann, Anthony Gavalas
This paper generates and validates hES cell reporter lines to monitor islet-like cluster differentiation and maturation, finding that N21 supplement improves monohormonal β-cell numbers.
Scientific Reports · Aug 27, 2024Peer-reviewedDevelopmental Biology