Katrin Neumann

The paper uses cerebral organoids from patients with actin mutations to show that altered cleavage plane orientation in ventricular zone progenitors leads to microcephaly.

This study shows MLL2 stabilizes 3D chromatin loops during pluripotent cell differentiation without requiring its enzymatic activity.

This paper generates and validates hES cell reporter lines to monitor islet-like cluster differentiation and maturation, finding that N21 supplement improves monohormonal β-cell numbers.

This study identifies signaling pathways that enable the unlimited expansion of human pancreatic progenitors in defined conditions, leading to efficient and reproducible cell production for diabetes research and therapies.

This study shows that human photoreceptor cells transplanted into human retina organoids integrate structurally, forming clusters with cone and rod photoreceptors and host cell contacts.

The paper investigates how native enhancers interact with promoters to shape cell-type-specific gene expression and shows that enhancers can regulate both developmental and housekeeping genes.

This study identifies that human axial progenitors generate trunk neural crest cells and defines their molecular signatures.