SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells
Véronique Fischer, Vincent Hisler, Elisabeth Scheer, Elisabeth Lata, Bastien Morlet, Damien Plassard, Dominique Helmlinger, Didier Devys, Làszlò Tora, Stéphane D. Vincent
This study shows that SUPT3H is not essential for SAGA complex assembly or overall Pol II transcription but is required for mESC growth and self-renewal.
Nucleic Acids Research · Jul 24, 2022Peer-reviewedMolecular Biology