Didier Devys

This study shows that SUPT3H is not essential for SAGA complex assembly or overall Pol II transcription but is required for mESC growth and self-renewal.

This study shows that USP22 and ATXN7L3 are essential for mouse development, with distinct roles, and that H2Bub1 deubiquitylation does not globally regulate RNA polymerase II transcription.

The paper improves the ChEC-seq method to more accurately map transcription coactivators and transcription factors' genome-wide DNA binding sites.

The paper shows that Med14 and Med17 subunits of the Mediator complex are essential for transcription in yeast, with Med17 having a more severe impact.

This study shows the INO80 complex helps RNA Polymerase II move past stalled positions, aiding non-coding RNA termination in yeast.

The paper shows that the Mediator complex is required for sn/snoRNA transcription in yeast, similar to its role in mRNA transcription.