Inference and validation of a dynamic gene regulatory network influencing cell fate during Duchenne muscular dystrophy initiation
Elsa Gratianne Guillot, Quentin Fort, Elise Mozin, Bérangère Robert, Matteo Bouvier, Cynthia Fourgeux, Paul Simon, Sara Munoz, Matthew Carter Childers, Jérémie Poschmann, Oumeya Adjali, David L. Mack, Arnaud Bonnaffoux, Jean-Baptiste Dupont
The paper identifies a dynamic gene regulatory network in Duchenne muscular dystrophy that controls cell fate decisions and shows how disease mutations disrupt this network.
bioRxiv · Nov 19, 2025 · PreprintBioinformatics