Ambroxol displaces α-synuclein from the membrane and inhibits the formation of early protein-lipid coaggregates
Jesper E. Dreier, Alisdair Stevenson, Elliot Carles, Katharina Schott, Thomas C. T. Michaels, Céline Galvagnion
This study shows Ambroxol inhibits α-synuclein-lipid coaggregation by displacing α-synuclein from membranes and preventing early coaggregate formation in GBA mutation models.
Chemical Science · Oct 31, 2025Peer-reviewedBiophysics