Author

Elodie Sins

Queen Mary University of London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Aashika SekariD· 1 shared Alberto RizzoiD· 1 shared Alexander D. FulfordiD· 1 shared Alexander Howard· 1 shared Beate M. LichtenbergeriD· 1 shared Benjamin P. FlynniD· 1 shared Bertram AschenbrenneriD· 1 shared Caterina MisseroiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Aashika SekarORCID

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2 papers

Recent·Most cited

YAP engages RIF1 to dampen replication stress-induced DNA damage in human squamous cell carcinoma.

Jodie Bojko, Elodie Sins, Benjamin P. Flynn, James A. Scarth, Mikal Negasi, Bertram Aschenbrenner, Molly Guscott, Alexander Howard, Emily Lay, Emma Bailey, Natalia Krajic, Marco Franciosi, Sandra Catalán Jiménez, Kelli Gallacher, Ilaria Di Girolamo, , Gernot Walko

This study identifies YAP's interaction with RIF1 in squamous cell carcinoma, showing it reduces replication stress-induced DNA damage through non-transcriptional mechanisms.

bioRxiv · Dec 20, 2024 · PreprintCancer Biology

A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation

Aashika Sekar, Alberto Rizzo, Elodie Sins, Alexander D. Fulford, Paulo S. Ribeiro

This study shows that PP2AWrd activates Hippo signaling by stabilizing Expanded, contrasting with PP2ACka's inhibitory role, and reveals interactions with Kibra and Crumbs in regulating Expanded proteostasis.

bioRxiv · Nov 14, 2024 · PreprintDevelopmental Biology