Author

Emily E. Brown

University of Pittsburgh

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Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Amanda M. GleixneriD· 1 shared Bryan T. Hurtle· 1 shared Christopher J. DonnellyiD· 1 shared Cristian A BergmanniD· 1 shared Edward B. LeeiD· 1 shared Evangelos KiskinisiD· 1 shared Feilin LiuiD· 1 shared Gabriela GrigoreaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Amanda M. GleixnerORCID

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1 paper

Recent·Most cited

Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD

Longxin Xie, Yuehua Zhu, Bryan T. Hurtle, Matthew Wright, John L. Robinson, Jocelyn C. Mauna, Emily E. Brown, Marilyn Ngo, Cristian A Bergmann, Jiazhen Xu, Jessica Merjane, Amanda M. Gleixner, Gabriela Grigorean, Feilin Liu, Wilfried Rossoll, , Christopher J. Donnelly

The paper identifies context-dependent interactors of TDP-43 that regulate its dysfunction in ALS/FTLD using proximity labeling, mass spectrometry, and snRNA-seq integration.

bioRxiv · Apr 7, 2025 · PreprintMolecular Biology