Netrin G1 Ligand is a new stromal immunomodulator that promotes pancreatic cancer
Debora Barbosa Vendramini Costa, Ralph Francescone, Janusz Franco‐Barraza, Tiffany Luong, Myree Graves, Ariana Musa de Aquino, Nina G. Steele, Jaye C. Gardiner, Sérgio Alexandre Alcântara dos Santos, Charline Ogier, Emily Malloy, Leila Borghaei, Esteban Martı́nez, Dmitry I. Zhigarev, Yinfei Tan, , Edna Cukierman
This paper identifies NGL-1 as a stromal immunomodulator in pancreatic cancer that promotes tumor growth by modulating the tumor microenvironment through TGF-β and transcription factor pathways.
bioRxiv · May 15, 2024 · PreprintCancer Biology