Control of cellular cortical tension and shape by RhoGTPase signalling
Pierre Bohec, Diana Khoromskaia, Manasi Kelkar, Emma C. Ferber, Guillaume Duprez, Geneviève Lavoie, Léo Valon, Philippe P. Roux, Guillaume Salbreux, Guillaume Charras
This study quantifies how RhoGTPase signalling controls cortical tension and cell shape using optogenetics and develops a predictive model linking signal gradients to mechanical changes.
bioRxiv · Mar 10, 2026 · PreprintBiophysics