Author

Guillaume Duprez

Lyon 1 UniversitéORCID 0009-0000-8159-0396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Charlotte RivièreiD· 1 shared Diana KhoromskaiaiD· 1 shared Emma C. Ferber· 1 shared Estelle BastieniD· 1 shared Geneviève Lavoie· 1 shared Guillaume CharrasiD· 1 shared Guillaume SalbreuxiD· 1 shared Hélène Delanoë‐AyariiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Charlotte RivièreORCID

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2 papers

Recent·Most cited

Control of cellular cortical tension and shape by RhoGTPase signalling

Pierre Bohec, Diana Khoromskaia, Manasi Kelkar, Emma C. Ferber, Guillaume Duprez, Geneviève Lavoie, Léo Valon, Philippe P. Roux, Guillaume Salbreux, Guillaume Charras

This study quantifies how RhoGTPase signalling controls cortical tension and cell shape using optogenetics and develops a predictive model linking signal gradients to mechanical changes.

bioRxiv · Mar 10, 2026 · PreprintBiophysics

Pore-size dynamics control complex volume swelling in pyroptosis.

Estelle Bastien, Guillaume Duprez, Hélène Delanoë‐Ayari, Hubert B. Leloup, Charlotte Rivière, Virginie Pétrilli, Pierre Recho, Sylvain Monnier

This study shows that pore-size dynamics in pyroptosis control cell swelling through GSDMD and Ninj1, with distinct permeability regimes affecting ion selectivity and water filtration.

Proceedings of the National Academy of Sciences · Jan 23, 2026Peer-reviewedBiophysics