Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models.
Isabel Castanho, Tracey K. Murray, Eilis J. Hannon, Aaron R. Jeffries, Emma Walker, Emma Laing, Hedley Baulf, Joshua Harvey, Andrew D. Randall, Karen Moore, Paul O’Neill, Katie Lunnon, David Andrew Collier, Zeshan Ahmed, Michael J. O’Neil, Jonathan S. Mill
This study identifies transcriptional changes in tau and amyloid mouse models, revealing gene expression patterns linked to AD pathology and immune response.
bioRxiv · Feb 13, 2019 · PreprintGenomics