Andrew D. Randall

This study investigates synaptic inputs to the retrosplenial cortex, finding that all recorded pyramidal neurons receive input from the anterior thalamic nuclei, with stronger responses compared to other sources.

This study examines network impairments in APPNL-G-F mice during sleep, finding NREM-specific changes in mPFC spindles and hippocampal SWRs linked to PV interneuron dysfunction.

The paper investigates beta bursting in the retrosplenial cortex of mice, finding it correlates with environmental novelty and is disrupted in a mouse model of Alzheimer's disease.

The paper examines speed encoding deficits in a tauopathy mouse model, finding impaired grid cell periodicity and disrupted speed-related firing rates in the medial entorhinal cortex.

The paper examines neurophysiological changes in the nucleus reuniens of J20 mice, finding hyperpolarized membrane potentials and altered rebound firing without changes in action potential generation.

The paper examines how Aβ plaques develop and affect synaptic density and turnover in a mouse model of Alzheimer's disease, finding an imbalance in pre- and post-synaptic responses.

This study identifies transcriptional changes in tau and amyloid mouse models, revealing gene expression patterns linked to AD pathology and immune response.

This study shows that human astrocytes increase fatty acid oxidation under recurrent low glucose to maintain nucleotide levels, indicating mitochondrial dysfunction in hypoglycemia response.

The paper shows that spinal and prefrontal projecting locus coeruleus neurons in rats mediate distinct pain-related behaviors: analgesia vs. aversion and anxiety.