The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus.
Joseph C. Ward, Lidia Lasecka‐Dykes, Chris Neil, Oluwapelumi O. Adeyemi, Sarah Gold, Niall McLean-Pell, Caroline F. Wright, Morgan R. Herod, David Kealy, Emma Warner, Terry Jackson, Donald P. King, Tobias J. Tuthill, David J. Rowlands, Nicola J. Stonehouse
This study shows that RNA pseudoknots in FMDV are not required for genome replication but are essential for producing infectious virus.
PLoS Pathogens · Jun 6, 2022Peer-reviewedMolecular Biology