Joseph C. Ward

This study identifies DNA methylation differences between microsatellite stable and microsatellite instable colorectal cancers, revealing MLH1-independent markers of mismatch repair deficiency and the impact of anatomical location.

This study shows that germline MUTYH haploinsufficiency increases mutational signature SBS18 and CRC risk, but not other cancers, due to oxidative DNA damage in the colorectum.

This study investigates the role of the conserved S fragment in FMDV replication using SHAPE and genomic analyses, revealing its structural importance and interaction with 3Dpol.

The paper introduces a method to distinguish viral RNA strands and investigates the role of cis-acting elements in FMDV replication.

This study shows that RNA pseudoknots in FMDV are not required for genome replication but are essential for producing infectious virus.