Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation
Nicholas J. Hanovice, Lyndsay L. Leach, Kayleigh Slater, Ana E. Gabriel, Dwight K. Romanovicz, Enhua Shao, Ross F. Collery, Edward A. Burton, Kira L. Lathrop, Brian A. Link, Jeffrey M. Gross
This study demonstrates that zebrafish can regenerate a functional RPE monolayer after widespread RPE ablation, with regeneration originating from peripheral RPE cells and requiring Wnt signaling.
PLoS Genetics · Jan 29, 2019Peer-reviewedDevelopmental Biology