Targeting the expansion of myeloid-derived suppressor cells in liver cirrhosis
Emilio Flint, Caner Ercan, Eoin Mitchell, Oltin T. Pop, Anne Geng, Paul OG Jorzik, Lucia A. Possamai, Robert G. Brenig, S. Morel, Pablo Sieber, Arjuna Singanayagam, Matthias Sebastian Matter, David Semela, Markus Hermann Heim, Philippe Demougin, , Christine Bernsmeier
This study investigates MDSC expansion in cirrhosis patients and murine models, showing poly(I:C) reduces MDSC and fibrosis in infected fibrotic mice.
bioRxiv · Mar 29, 2024 · PreprintImmunology