Markus Hermann Heim

This paper identifies a distinct HCC subgroup defined by high regeneration-associated stress, showing vulnerability to ATR inhibitors and proposing LIVRESS as a biomarker for treatment stratification.

The paper identifies CD52-expressing monocytes in cirrhosis that enhance innate immunity, but their loss during acute decompensation correlates with infection and poor outcomes.

This study performs a meta-analysis of lncRNA associations with hepatocellular carcinoma, finding limited reproducibility and frequent conflicts in reported roles and expression patterns.

This study investigates MDSC expansion in cirrhosis patients and murine models, showing poly(I:C) reduces MDSC and fibrosis in infected fibrotic mice.

The paper introduces bnClustOmics, a Bayesian network mixture model for multi-omics clustering, identifies three HCC subtypes with survival associations, and learns cluster-specific molecular networks.