Author

Philippe Demougin

University of BaselORCID 0009-0002-2820-9909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Julien RouxiD· 2 shared Anna Lena KastneriD· 1 shared Anna‐Friederike MarxiD· 1 shared Anne GengiD· 1 shared Arjuna SinganayagamiD· 1 shared Caner ErcaniD· 1 shared Christine BernsmeieriD· 1 shared Daniel D. PinscheweriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Julien RouxORCID

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2 papers

Recent·Most cited

Chronic Infection Perturbs the Affinity Hierarchy of Antiviral B Cells

Mirela Dimitrova, Tiago Abreu-Mota, Jonas Fixemer, Weldy V. Bonilla, Anna‐Friederike Marx, Min Lu, Karen Tintignac, Anna Lena Kastner, Yusuf I. Ertuna, Marianna Florova, Matías Ciancaglini, Kerstin Narr, Karsten Stauffer, Julien Roux, Philippe Demougin, , Daniel D. Pinschewer

This study shows that chronic viral infection disrupts B cell affinity hierarchies by preferentially causing attrition of high-affinity B cells due to excessive antigen stimulation.

bioRxiv · Aug 21, 2025 · PreprintImmunology

Targeting the expansion of myeloid-derived suppressor cells in liver cirrhosis

Emilio Flint, Caner Ercan, Eoin Mitchell, Oltin T. Pop, Anne Geng, Paul OG Jorzik, Lucia A. Possamai, Robert G. Brenig, S. Morel, Pablo Sieber, Arjuna Singanayagam, Matthias Sebastian Matter, David Semela, Markus Hermann Heim, Philippe Demougin, , Christine Bernsmeier

This study investigates MDSC expansion in cirrhosis patients and murine models, showing poly(I:C) reduces MDSC and fibrosis in infected fibrotic mice.

bioRxiv · Mar 29, 2024 · PreprintImmunology