Author

Ergina Vourkou

Alexander Fleming Biomedical Sciences Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessia SantambrogioiD· 1 shared Byron W. CaugheyiD· 1 shared Dillon J. RinauroiD· 1 shared Efthimios M. C. SkoulakisiD· 1 shared Katerina PapanikolopoulouiD· 1 shared Michael A. MetrickiD· 1 shared Michele VendruscoloiD· 1 shared Nicholas C. T. Gallagher· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alessia SantambrogioORCID

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1 paper

Recent·Most cited

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

Alessia Santambrogio, Robert I. Horne, Michael A. Metrick, Nicholas C. T. Gallagher, Z. Faidon Brotzakis, Dillon J. Rinauro, Ergina Vourkou, Katerina Papanikolopoulou, Efthimios M. C. Skoulakis, Sara Snogerup Linse, Byron W. Caughey, Michele Vendruscolo

The paper develops an in vitro tau aggregation assay combined with machine learning to identify polymorph-specific tau inhibitors, validated in a Drosophila model.

Journal of the American Chemical Society · Sep 18, 2025Peer-reviewedBiophysics