Author

Nicholas C. T. Gallagher

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Michael A. MetrickiD· 2 shared Michele VendruscoloiD· 2 shared Alessia SantambrogioiD· 1 shared Alessia SantambrogioiD· 1 shared Bernardino Francesco GhettiiD· 1 shared Byron Caughey· 1 shared Byron W. CaugheyiD· 1 shared Dillon J. RinauroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Michael A. MetrickORCID

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2 papers

Recent·Most cited

NeuroscienceFEBS LettersPeer-reviewedSep 30, 2025

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

Alessia Santambrogio, Sofia Lövestam, Michael A. Metrick…·Michele Vendruscolo

This study investigates tau filament assembly using mutant recombinant tau and brain homogenates, finding that specific mutations produce filaments resembling AD pathology.

4 citations

humanprotein structure

𝕏 PostBluesky

BiophysicsJournal of the American Chemical SocietyPeer-reviewedSep 18, 2025

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

Alessia Santambrogio, Robert I. Horne, Michael A. Metrick…·Michele Vendruscolo

The paper develops an in vitro tau aggregation assay combined with machine learning to identify polymorph-specific tau inhibitors, validated in a Drosophila model.

12 citationstop 2%

Drosophilaproteomics

𝕏 PostBluesky