A shark variable new antigen receptor recognizes an occluded epitope of fibroblast activation protein
Roma Broadberry, Kendahl L. Ott, Eric Lake, T. Ravi, Colin A. Hemme, 郗商, Jayden L. West, Gihan S. Gunaratne, Irene M. Ong, Aaron Matthew LeBeau, Timothy Grant
This study identifies a shark-derived VNAR that binds a hidden epitope on FAP, revealing structural insights for multiepitope targeting strategies.
bioRxiv · Aug 12, 2026 · PreprintBiochemistry