Author

Colin A. Hemme

University of Wisconsin–MadisonORCID 0000-0003-4133-3103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Timothy GrantiD· 2 shared Aaron Matthew LeBeauiD· 1 shared Alexander ThomeiD· 1 shared Chad M. RienstraiD· 1 shared Christopher G. WilliamsiD· 1 shared Eric Lake· 1 shared Gihan S. GunaratneiD· 1 shared Irene M. OngiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Timothy GrantORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 12, 2026

A shark variable new antigen receptor recognizes an occluded epitope of fibroblast activation protein

Roma Broadberry, Kendahl L. Ott, Eric Lake…·Timothy Grant

This study identifies a shark-derived VNAR that binds a hidden epitope on FAP, revealing structural insights for multiepitope targeting strategies.

DOI 10.64898/2026.08.11.744296

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BiophysicsAnalytical ChemistryPeer-reviewedDec 15, 2025

NMR Spectral Alignment Utilizing a CryoEM Motion Correction Algorithm

Colin A. Hemme, Owen A. Warmuth, Songlin Wang…·Timothy Grant

This paper introduces ANSA, an automated NMR spectral alignment tool using cryo-EM motion correction, improving alignment accuracy and reducing manual effort in NMR data processing.

DOI 10.1021/acs.analchem.5c02504

deep learningbenchmarking

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