Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts
Jackie Chen, Erick D. Nilsen, Chutikarn Chitboonthavisuk, James E. Corban, Matthew Yang, Charlie Y. Mo, Srivatsan Raman
This study introduces PhageMaP, a high-throughput method to assess gene essentiality in bacteriophages across diverse hosts and uses it to engineer synthetic phages with enhanced infectivity.
Cell Host & Microbe · Oct 11, 2024Peer-reviewedMicrobiology