Chutikarn Chitboonthavisuk

Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts

This study introduces PhageMaP, a high-throughput method to assess gene essentiality in bacteriophages across diverse hosts and uses it to engineer synthetic phages with enhanced infectivity.

Systematic genome-wide discovery of host factors governing bacteriophage infectivity

The paper introduces PHAGEPACK, a CRISPR-based assay to systematically identify host genes affecting phage infectivity, revealing new pathways in both permissive and non-permissive E. coli.

Bacteriophage-host interactions in microgravity aboard the International Space Station

This study examines T7 bacteriophage and E. coli interactions in microgravity, finding delayed initial phage activity but eventual success with mutations enhancing fitness and revealing differences in mutational preferences.

Engineering a dynamic, controllable infectivity switch in bacteriophage T7

This study engineers a controllable infectivity switch in bacteriophage T7 using synthetic promoters and ribosome binding sites, showing tunable virulence and latency.