Sleep Facilitates Pattern Separation through SK Channel-Mediated Sparse Coding
Chien-Chun Chen, Yu-Chun Huang, Antonio Ortega, Raquel Suárez-Grimalt, Erik Tedre, El‐Sayed Baz, Yifan Wu, Andrew C. Lin, Sha Liu
This study shows that sleep deprivation in Drosophila impairs pattern separation by disrupting sparse coding in the mushroom body through SK channel-mediated changes in inhibitory neurons.
Current Biology · Mar 16, 2026Peer-reviewedNeuroscience