Chien-Chun Chen

This study shows that sleep deprivation in Drosophila impairs pattern separation by disrupting sparse coding in the mushroom body through SK channel-mediated changes in inhibitory neurons.

The paper shows that presynaptic release probability, not synaptic strength, decreases with sleep loss and affects sleep need across species.

The paper introduces iDOC, a platform for single-fly olfactory conditioning and memory assessment, showing spaced training promotes sleep while massed training induces anesthesia-resistant memory.