Raquel Suárez-Grimalt

Sleep Facilitates Pattern Separation through SK Channel-Mediated Sparse Coding

This study shows that sleep deprivation in Drosophila impairs pattern separation by disrupting sparse coding in the mushroom body through SK channel-mediated changes in inhibitory neurons.

Coherent multi-level network oscillations create neural filters to favor quiescence over navigation in Drosophila

The paper shows how coherent neural oscillations in Drosophila create filters that promote quiescence over navigation by hierarchically overriding locomotion-promoting networks.

Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive memories in Drosophila

This study shows that postsynaptic plasticity at cholinergic synapses in Drosophila mushroom bodies is essential for appetitive memory induction but not aversive memories.

Localized inhibition in the Drosophila mushroom body

The paper shows that APL inhibits Kenyon cells locally in both dendrites and axons, enabling differential inhibition across mushroom body compartments.

Network-specific synchronization of electrical slow-wave oscillations regulates sleep in Drosophila

The paper identifies delta oscillations in Drosophila's R2 network that regulate sleep, showing synchronization depends on NMDARs and input pathways, and disrupting this mechanism abolishes oscillations and impairs sleep.