Author

Erika M. McCown

City Of Hope National Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Debbie C. ThurmondiD· 3 shared Eunjin OhiD· 3 shared Adolfo Garcı́a-OcañaiD· 1 shared Angelica Hamilton· 1 shared Chelsea Jang· 1 shared Chun‐Xue ZhouiD· 1 shared Diana Esparza· 1 shared Diti Chatterjee Bhowmick· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Debbie C. ThurmondORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 28, 2026

Role of Uridine Phosphorylase 1 (UPP1) in Pancreatic β-Cell Physiology and Its Dysregulation in Obesity and Type 2 Diabetes

YUNQIAN PENG, Lu Ding, Qiutang Xiong…·Yingfeng Deng

This study investigates the role of UPP1 in β-cell function and shows that UPP1 deficiency impairs uridine-potentiated GSIS and MAPK activation in mice and humans.

DOI 10.64898/2026.09.24.754194

mousehuman

PhysiologybioRxivPreprintJan 6, 2026

Loss of Exocytosis Protein DOC2B is an Early Event in Type 1 Diabetes Development

Diana Esparza, Eunjin Oh, Jinhee H Hwang…·Debbie C. Thurmond

The paper identifies DOC2B decline as an early biomarker of presymptomatic type 1 diabetes progression, preceding traditional markers like C-peptide and HbA1c.

1 citation

humanmouse

Cell BiologyJournal of Cachexia Sarcopenia and MusclePeer-reviewedNov 10, 2025

STX4 is indispensable for mitochondrial homeostasis in skeletal muscle

Joseph M. Hoolachan, Rekha Balakrishnan, Erika M. McCown…·Debbie C. Thurmond

This study shows STX4 is essential for mitochondrial homeostasis in skeletal muscle by regulating mitochondrial biogenesis and mitophagy.

3 citations

mouseproteomics