rTg(TauP301L)4510 mice exhibit increased VGLUT1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release
Erika Taipala, Jeremiah C. Pfitzer, Morgan Hellums, Miranda Nicole Reed, Michael W. Gramlich
This study shows that increased extracellular glutamate in tauP301L mice is due to higher VGLUT1 per synaptic vesicle, not increased exocytosis.
Frontiers in Synaptic Neuroscience · Aug 3, 2022Peer-reviewedNeuroscience