Author

Erin C. Connolly

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Allyson E. Koyen· 1 shared Anna Marie KenneyiD· 1 shared B WuiD· 1 shared Bing YaoiD· 1 shared Blerta XhemalçeiD· 1 shared Boya Gao· 1 shared Boying S. Song· 1 shared Carrie J. ShawberiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Allyson E. Koyen

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Author profile →

3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJul 23, 2026

HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous recombination repair

Ramona Haji‐Seyed‐Javadi, Allyson E. Koyen, Sandip Kumar Rath…·David S. Yu

This study identifies HELZ as an RNA-DNA helicase that resolves R loops to support homologous recombination repair and genomic stability.

4 citations

humanexperimental assay

Cancer BiologybioRxivPreprintJun 1, 2026

A Novel Therapeutic Approach: Gamma Secretase Inhibitor Enhances Radiotherapy and Checkpoint Blockade Therapy via Reprogramming of the Tumor Microenvironment

Q. Wang, Debarshi Banerjee, Erin C. Connolly…·Eileen P. Connolly

This study shows that combining gamma secretase inhibitor with radiotherapy and checkpoint blockade therapy reprograms the tumor microenvironment to enhance antitumor immunity.

DOI 10.64898/2025.12.30.696685

mouseflow cytometry

BioinformaticsbioRxivPreprintJun 15, 2023

Acceleration of Large-Scale Single Cell Differential Gene Expression Analysis with FastDE

Erin C. Connolly, Maneesha R. Aluru, Sriram P. Chockalingam…·Tony C Pan

FastDE accelerates differential gene expression analysis in single-cell data by 50X, replicating age and gender effects on immune cell differentiation in PBMC atlases.

DOI 10.1101/2023.06.15.545003