Author

David S. Yu

Emory UniversityORCID 0000-0002-2781-5379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Lily P H YangiD· 2 shared Allyson E. Koyen· 1 shared Anna Marie KenneyiD· 1 shared B WuiD· 1 shared Bing YaoiD· 1 shared Blerta XhemalçeiD· 1 shared Boya Gao· 1 shared Boying S. Song· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Lily P H YangORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJul 23, 2026

HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous recombination repair

Ramona Haji‐Seyed‐Javadi, Allyson E. Koyen, Sandip Kumar Rath…·David S. Yu

This study identifies HELZ as an RNA-DNA helicase that resolves R loops to support homologous recombination repair and genomic stability.

4 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 1, 2025

A novel 18F-labeled brain penetrant PET ligand for imaging poly(ADP-ribose) polymerase-1

Jimmy S. Patel, Xin Mu Zhou, Jiahui Chen…·Steven H. Liang

This paper evaluates [18F]AZD9574, a PET radiotracer for imaging PARP-1, showing uptake correlated with PARP-1 expression and blocked by PARP inhibitors in cancer cell lines and xenograft models.

1 citation

𝕏 PostBluesky