DC-SIGN Binding to the Surface Ig Oligomannose-type Glycans Promotes Follicular Lymphoma Cell Adhesion and Survival
Giorgia Chiodin, Dylan J. Tatterton, Philip J. Rock, Luis Del Rio, Erin Snook, Sonya James, Patrick J. Duriez, Miriam Di Re, Martijn Verdoes, Stuart Lanham, Daniel James Hodson, Richard W. Burack, Francesco Forconi
This study shows that DC-SIGN binding to sIg-Mann on follicular lymphoma cells promotes adhesion to VCAM-1 and survival, suggesting a therapeutic target for FL.
Blood · Jan 20, 2026Peer-reviewedCancer Biology