Martijn Verdoes

This study shows that DC-SIGN binding to sIg-Mann on follicular lymphoma cells promotes adhesion to VCAM-1 and survival, suggesting a therapeutic target for FL.

This study shows that galectin-9 in dendritic cells is necessary for organizing HLA-II at immune synapses, which enhances CD4+ T cell activation and anti-tumor immunity.

This study shows that inhibiting SHP-1/2 reduces antigen cross-presentation by macrophages and dendritic cells, potentially limiting the effectiveness of PD-1 checkpoint therapy.

This study compares three nuclear imaging methods to quantify CD8+ T-cell infiltration in tumors, finding that two methods correlate with CD8+ T-cell counts while showing different distribution patterns.

The paper investigates the impact of elevated cystatin B on cathepsin B activity and microglial localization in Alzheimer's disease in Down syndrome and early-onset Alzheimer's disease.