BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu
Charles K. Min, Jerome C. Nwachukwu, Yingwei Hou…·K. W. Nettles
This paper shows that estrogen receptor-α homodimers can function as conformational heterodimers, integrating different ligand signals to produce distinct agonist or antagonist activity profiles.
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