Jian Min

The paper reports the structure of SoP450, a self-sufficient cytochrome P450, revealing its dimeric form and electron transfer mechanism.

This study reports the cryo-EM structures of Geobacillus stearothermophilus Cas9 complexed with sgRNA and target DNA, revealing the catalytic mechanism and thermal stability features.

This paper shows that estrogen receptor-α homodimers can function as conformational heterodimers, integrating different ligand signals to produce distinct agonist or antagonist activity profiles.