Transcript architecture sets the m6A landscape: CSTF2 and CSTF2T reshape m6A through cleavage-dependent and -independent mechanisms
Caroline J. Aufgebauer, Theodore M. Nelson, Nadia Houerbi, Seth D. Veenbaas, Matthew Tegowski, Esther Luo, Enakshi Sivasudhan, Michael Goneos, Paul G. Collier, Jacqueline Proszynski, Krista A. Ryon, Evan M Violette, Savanna A. Touré, Kate D. Meyer, Christopher E. Mason, Stacy M. Horner
The paper identifies CSTF2 and CSTF2T as factors that shape the m6A landscape through cleavage-dependent and -independent mechanisms by altering transcript architecture and polyadenylation sites.
bioRxiv · Jun 8, 2026 · PreprintMolecular Biology