Author

Seth D. Veenbaas

University of North Carolina at Chapel HillORCID 0009-0003-5786-0407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kevin M. WeeksiD· 2 shared Caroline J. AufgebaueriD· 1 shared Christopher E. MasoniD· 1 shared Enakshi SivasudhaniD· 1 shared Esther Luo· 1 shared Evan M VioletteiD· 1 shared Jacqueline Proszynski· 1 shared Jordan T. KoehniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Kevin M. WeeksORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 8, 2026

Transcript architecture sets the m6A landscape: CSTF2 and CSTF2T reshape m6A through cleavage-dependent and -independent mechanisms

Caroline J. Aufgebauer, Theodore M. Nelson, Nadia Houerbi…·Stacy M. Horner

The paper identifies CSTF2 and CSTF2T as factors that shape the m6A landscape through cleavage-dependent and -independent mechanisms by altering transcript architecture and polyadenylation sites.

DOI 10.64898/2026.03.27.714597

long-read sequencingstatistical model

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BioinformaticsACS Chemical BiologyPeer-reviewedDec 17, 2025

fpocketR: A platform for identification and analysis of ligand-binding pockets in RNA

Seth D. Veenbaas, Simon Felder, Kevin M. Weeks

fpocketR identifies and analyzes ligand-binding pockets in RNA structures to discover potential drug targets.

7 citations

protein structureexperimental assay

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedApr 22, 2025

Ligand-binding pockets in RNA, and where to find them

Seth D. Veenbaas, Jordan T. Koehn, Patrick S. Irving…·Kevin M. Weeks

This paper introduces fpocketR to detect RNA ligand-binding pockets and validates them with Frag-MaP, identifying new sites capable of binding drug-like ligands.

28 citationstop 1%

protein structuredeep learning

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