Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
Andrew Murley, Ann Catherine Popovici, Xiaozhou Hu, Anina Lund, Kevin Wickham, Jenni Durieux, Larry K. Joe, Etai Koronyo, Hanlin Zhang, Naomi R. Genuth, Andrew G. Dillin
This study shows that macroautophagy-induced lysosomal damage limits quiescent cell re-entry, and reducing this damage can enhance cell cycle re-entry in C. elegans and mammalian cells.
Cell · Apr 8, 2025Peer-reviewedCell Biology