Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors
Eunkyu Sung, Shohei Murakami, Masanobu Morita, Tomoaki Ida, Takaaki Akaike, Hozumi Motohashi
The paper shows that mitochondrial content influences lineage commitment in megakaryocyte-erythroid progenitors, with mitochondria-rich cells favoring erythroid differentiation and mitochondria-poor cells favoring megakaryocyte differentiation.
Stem Cell Reports · Nov 20, 2025Peer-reviewedCell Biology