Author

Masanobu Morita

Tohoku UniversityORCID 0000-0002-5259-5371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Hozumi MotohashiiD· 3 shared Takaaki AkaikeiD· 3 shared Tomoaki IdaiD· 3 shared Tetsuro MatsunagaiD· 2 shared Tsuyoshi TakataiD· 2 shared Akira NishimuraiD· 1 shared Ayumi MitsuneiD· 1 shared Ayumi SuzukiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

Hozumi MotohashiORCID

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3 papers

Recent·Most cited

Sulfide:quinone oxidoreductase drives mitochondrial supersulfide metabolism to regulate bioenergetics and longevity in eukaryotes

Jia Yao, Tetsuro Matsunaga, Akira Nishimura, Meg Shieh, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Tsuyoshi Takata, Uladzimir Barayeu, Hozumi Motohashi, Masanobu Morita, Takaaki Akaike

This study shows that SQR is essential for mitochondrial function and longevity by regulating sulfur respiration and supersulfide metabolism in yeast and mice.

bioRxiv · Apr 7, 2026 · PreprintBiochemistry

Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors

Eunkyu Sung, Shohei Murakami, Masanobu Morita, Tomoaki Ida, Takaaki Akaike, Hozumi Motohashi

The paper shows that mitochondrial content influences lineage commitment in megakaryocyte-erythroid progenitors, with mitochondria-rich cells favoring erythroid differentiation and mitochondria-poor cells favoring megakaryocyte differentiation.

Stem Cell Reports · Nov 20, 2025Peer-reviewedCell Biology

Glutathione supersulphide regulates T-cell receptor signalling

Yusaku Sasaki, Tadahisa Numakura, Mitsuhiro Yamada, Hisatoshi Sugiura, Tetsuro Matsunaga, Tomoaki Ida, Masanobu Morita, Ayumi Suzuki, Shuichiro Matsumoto, Madoka Kawaguchi, Takeshi Kawabe, Shunichi Tayama, Yuko Okuyama, Tsuyoshi Takata, Kenji Inaba, , Hozumi Motohashi

This study shows that glutathione supersulphide regulates T-cell receptor signalling by interacting with the CD3ε chain, affecting TCR activation and inflammation.

bioRxiv · Apr 30, 2024 · PreprintBiochemistry