Takaaki Akaike

This study shows that PfGrx rapidly reduces glutathione polysulfides, generating hydrogen sulfide and glutathionylated enzyme, with rate constants comparable to glutathione disulfide reduction.

This study shows that SQR is essential for mitochondrial function and longevity by regulating sulfur respiration and supersulfide metabolism in yeast and mice.

The paper shows that mitochondrial content influences lineage commitment in megakaryocyte-erythroid progenitors, with mitochondria-rich cells favoring erythroid differentiation and mitochondria-poor cells favoring megakaryocyte differentiation.

This study shows that SOX deficiency leads to persulfidation loss and increased H2S release, with thiosulfate accumulation and metabolic rewiring in a mouse model.

This study shows that glutathione supersulphide regulates T-cell receptor signalling by interacting with the CD3ε chain, affecting TCR activation and inflammation.