Author

Evan C. Hawthorn

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Assay:scRNA-seq· 4 Research Focus:gene regulatory network inference· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

Andy J. FischeriD· 5 shared Heithem M. El‐HodiriiD· 5 shared Warren A. CampbelliD· 3 shared Lisa E. Kelly· 2 shared Abhay R. SatoskariD· 1 shared Ali Zatari· 1 shared Allen Tangeman· 1 shared Archana JalligampalaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersNeuroscience

Andy J. FischerORCID

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Author profile →

5 papers

Recent·Most cited

Ibudilast Protects Retinal Bipolar Cells from Excitotoxic Retinal Damage and Activates the mTOR Pathway

Sumaya Hamadmad, Tyler Heisler‐Taylor, Sandeep Goswami, Evan C. Hawthorn, Sameer Chaurasia, Dena Martini, Diana Summitt, Ali Zatari, Rahaf Shalash, Misha Sohail, Elizabeth G Urbanski, Kayla Bernstein, Julie Racine, Abhay R. Satoskar, Heithem M. El‐Hodiri, , Colleen M. Cebulla

This study shows ibudilast protects retinal bipolar cells from excitotoxic damage by upregulating mTOR signaling and other pathways, with potential for clinical application.

Glia · Feb 6, 2025Peer-reviewedNeuroscience

ID transcription factors regulate the ability of Muller glia to become proliferating neurogenic progenitor-like cells

Olivia B. Taylor, Snehal P. Patel, Evan C. Hawthorn, Heithem M. El‐Hodiri, Andy J. Fischer

This study shows ID transcription factors regulate Muller glia reprogramming into progenitor cells after retinal damage by controlling p21Cip1 levels and neurogenic potential.

Glia · Mar 21, 2024Peer-reviewedNeuroscience

Chromatin access regulates the formation of Muller glia-derived progenitor cells in the retina

Warren A. Campbell, Heithem M. El‐Hodiri, Diego Torres, Evan C. Hawthorn, Lisa E. Kelly, Leo I. Volkov, David Akanonu, Andy J. Fischer

This study shows that SAHH and HMTs regulate chromatin access in chick retinas to reprogram Muller glia into progenitor cells, but not in mouse retinas.

Glia · Mar 27, 2023Peer-reviewedNeuroscience

Fatty acid-binding proteins and fatty acid synthase influence glial reactivity and promote the formation of Müller glia-derived progenitor cells in the avian retina

Warren A. Campbell, Allen Tangeman, Heithem M. El‐Hodiri, Evan C. Hawthorn, Maddie Hathoot, Sydney Blum, Thanh V. Hoang, Seth Blackshaw, Andy J. Fischer

This study investigates the role of fatty acid-binding proteins (FABPs) and fatty acid synthase (FASN) in glial reactivity and Müller glia-derived progenitor cell formation in the chick retina using scRNA-seq.

Development · Feb 8, 2022Peer-reviewedDevelopmental Biology

Nuclear Factor I in neurons, glia and during the formation of Muller glia-derived progenitor cells in avian, porcine and primate retinas

Heithem M. El‐Hodiri, Warren A. Campbell, Lisa E. Kelly, Evan C. Hawthorn, Maura Schwartz, Archana Jalligampala, Maureen A. McCall, Kathrin Meyer, Andy J. Fischer

This study examines the expression patterns of Nuclear Factor I (NFI) isoforms in retinas of chick, pig, and monkey, finding that NFIA and NFIB are expressed in developing and mature retinal cells, with reduced levels in proliferating Muller glia-derived progenitor cells.

The Journal of Comparative Neurology · Nov 3, 2021Peer-reviewedNeuroscience